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Systematic evaluation of structure–property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride

Derivative (Chemistry)Pharmaceutical ChemistryEngineeringPair AnalogsOrganic ChemistrySystematic EvaluationPharmacologyStructure–property RelationshipsBiomolecular Engineering