David M. Shackleford

Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

Susan A. Charman, Sarah Arbe‐Barnes, Ian Bathurst et al. · Proceedings of the National Academy of Sciences · 2011 · 376 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +14

Quinolone-3-Diarylethers: A New Class of Antimalarial Drug

Aaron Nilsen, Alexis N. LaCrue, Karen L. White et al. · Science Translational Medicine · 2013 · 302 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent<i>Plasmodium falciparum</i>Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

José M. Coterón, María Marco, Jorge Esquivias et al. · Journal of Medicinal Chemistry · 2011 · 284 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Antimalarial efficacy of MMV390048, an inhibitor of <i>Plasmodium</i> phosphatidylinositol 4-kinase

Tanya Paquet, Claire Le Manach, Diego González Cabrera et al. · Science Translational Medicine · 2017 · 272 citations · Full text

Medicine, Infectious Diseases, Pharmacology +16

Chronic stress accelerates pancreatic cancer growth and invasion: A critical role for beta-adrenergic signaling in the pancreatic microenvironment

Corina Kim-Fuchs, Caroline P. Le, Matthew A. Pimentel et al. · Brain Behavior and Immunity · 2014 · 270 citations · Full text

Medicine, Cancer Biology, Oncology +17