Theranostics · 2021 · 22 citations · 51 references
Life SciencesCell BiologyMolecular BiologyCell SignalingGene ExpressionSignal TransductionAngiogenesisEndothelial ActivationInnate Immune Signaling PathwaysNod-like ReceptorsDamage-associated Molecular PatternsNlr Family RegulationNlr SignalingNucleotide-binding Oligomerization Domain-like Receptor SignalingStat3 Signaling
In the ischemic microenvironment, NLRC5 protein accumulates in the nucleus of ECs and enhances STAT3 transcriptional activity for angiogenesis. These findings establish NLRC5 as a novel modulator of VEGFA signaling, providing a new target for angiogenic therapy to foster tissue regeneration.
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Molecular signatures database (MSigDB) 3.0
Arthur Liberzon, Aravind Subramanian, Reid M. Pinchback et al. · Bioinformatics · 2011 · 7.7K citations · Full text
Stat3 Dimerization Regulated by Reversible Acetylation of a Single Lysine Residue
Zhenglong Yuan, Yingjie Guan, Devasis Chatterjee et al. · Science · 2005 · 777 citations
Khandaker Siddiquee, Shumin Zhang, Wayne C. Guida et al. · Proceedings of the National Academy of Sciences · 2007 · 743 citations · Full text