Concepedia

E2F2 drives glioma progression via PI3K/AKT in a PFKFB4-dependent manner

Longzhou Zhang, Zengjin Liu, Dong Yang, Lingchang Kong

Life Sciences · 2021 · 40 citations · 18 references

DOI

Concepts

References

18

Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer

Subhamoy Dasgupta, Kimal Rajapakshe, Bokai Zhu et al. · Nature · 2018 · 263 citations

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PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis

Ji Liang, Ruixiu Cao, Yajuan Zhang et al. · Nature Communications · 2016 · 211 citations · Full text

, , +17

E2F2 directly regulates the STAT1 and PI3K/AKT/NF-κB pathways to exacerbate the inflammatory phenotype in rheumatoid arthritis synovial fibroblasts and mouse embryonic fibroblasts

Shiguan Wang, Lin Wang, Changshun Wu et al. · Arthritis Research & Therapy · 2018 · 77 citations · Full text

, , +17

Expression and prognostic role of E2F transcription factors in high‐grade glioma

Hai Yu, Zhijin Li, Maode Wang · CNS Neuroscience & Therapeutics · 2020 · 67 citations · Full text

, , +16

PFKFB4 controls embryonic patterning via Akt signalling independently of glycolysis

Caterina Pegoraro, Ana Leonor Figueiredo, Frédérique Maczkowiak et al. · Nature Communications · 2015 · 53 citations · Full text

, , +17