Concepedia

Publication | Open Access

Enhanced brain delivery and therapeutic activity of trastuzumab after blood-brain barrier opening by NEO100 in mouse models of brain-metastatic breast cancer

DOIFull Paper Access

28

Citations

24

References

2021

Year

Weijun Wang, Haiping He, Nagore I. Marín‐Ramos, Shan Zeng, Steven Swenson, Hee‐Yeon Cho, Jie Fu, Paul M. Beringer, Josh Neman, Ligang Chen,
Neuro-Oncology

Abstract

IA NEO100 facilitates brain tumor entry of trastuzumab and T-DM1 and significantly enhances their therapeutic efficacy, along with increased antibody-dependent immune cell recruitment.

References

YearCitations

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