Concepedia

Proteinase-Mediated Macrophage Signaling in Psoriatic Arthritis

Fatima Abji, Mozhgan Rasti, A. Gómez-Aristizábal, Carla Muytjens, Mahmoud Saifeddine, Koichiro Mihara, Majid Motahhari, Rajiv Gandhi, Sowmya Viswanathan, Morley D. Hollenberg,

Frontiers in Immunology · 2021 · 26 citations · 74 references

DOIFull text

Open access

Abstract

PAR2 and its activating proteinases, including tryptase-6, can be important mediators of inflammation in PsA. Components within this proteinase-receptor axis may represent novel therapeutic targets.

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