Sanhuang Jiangtang tablet protects type 2 diabetes osteoporosis via AKT-GSK3β-NFATc1 signaling pathway by integrating bioinformatics analysis and experimental validation

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Epidemiology of Type 2 Diabetes – Global Burden of Disease and Forecasted Trends

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Public Health, Health Sciences, Epidemiologic Methods +16

Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice

Hong Chen, Olga Charlat, Louis A. Tartaglia et al. · Cell · 1996 · 2.2K citations · Full text

Life Sciences, Endocrinology, Genetics +11

Leptin Inhibits Bone Formation through a Hypothalamic Relay

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Medicine, Endocrinology, Physiology +13

<b>A new method for the model‐independent assessment of thickness in three‐dimensional images</b>

T. Hildebrand, P. Rüegsegger · Journal of Microscopy · 1997 · 1.8K citations

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