Concepedia

Effects of Hsp90 inhibitor on the RIP1-RIP3-MLKL pathway during the development of heart failure in mice

Tetsuro Marunouchi, Chiharu Nishiumi, Saki Iinuma, Emi Yano, Kouichi Tanonaka

European Journal of Pharmacology · 2021 · 56 citations · 34 references

DOI

Concepts

References

34

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

Young-Sik Cho, Sreerupa Challa, David Moquin et al. · Cell · 2009 · 2.4K citations · Full text

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Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule

Nils Holler, Rossana Zaru, Olivier Micheau et al. · Nature Immunology · 2000 · 1.9K citations

, , +14

Apoptosis in the Failing Human Heart

G Olivetti, Rakesh Abbi, Federico Quaini et al. · New England Journal of Medicine · 1997 · 1.7K citations · Full text

, , +7

Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3

Huayi Wang, Liming Sun, Lijing Su et al. · Molecular Cell · 2014 · 1.6K citations · Full text

, , +7

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

Zhenyu Cai, Siriporn Jitkaew, Jie Zhao et al. · Nature Cell Biology · 2013 · 1.3K citations · Full text

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