Anti-cancer effect of metformin on the metastasis and invasion of primary breast cancer cells through mediating NF-kB activity

Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission

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Cancer Biology, Cancer Stem, Xenograft Mouse Model +16

Constitutive Activation of NF-κB during Progression of Breast Cancer to Hormone-Independent Growth

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Breast Oncology, Immunology, Transcription Factor Nf-kappab +20

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.

Ralf C. Bargou, Florian Emmerich, Daniel Krappmann et al. · Journal of Clinical Investigation · 1997 · 765 citations · Full text

Disease Tumor Cells, Constitutive Nuclear Nf-kappab, Immunology +16

NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4

Gregory M. Helbig, Kent W. Christopherson, Poornima Bhat‐Nakshatri et al. · Journal of Biological Chemistry · 2003 · 630 citations · Full text

Metformin inhibits the senescence‐associated secretory phenotype by interfering with <scp>IKK</scp>/<scp>NF</scp>‐κ<scp>B</scp> activation

Olga Moiseeva, Xavier Deschênes‐Simard, Emmanuelle St‐Germain et al. · Aging Cell · 2013 · 605 citations · Full text