Concepedia

Neuroprotective effect of hydrogen sulfide against glutamate-induced oxidative stress is mediated via the p53/glutaminase 2 pathway after traumatic brain injury

Jianping Sun, Xiaoyu Li, Xiaoyu Gu, Hailong Du, Gengshen Zhang, Jianliang Wu, Feng Wang

Aging · 2021 · 32 citations · 26 references

DOIFull text

Open access

Concepts

Abstract

S protects brain injury induced by TBI through modulation of the glutamate-mediated oxidative stress in the p53/GLS-2 pathway-dependent manner.

References

26

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

Wenwei Hu, Cen Zhang, Rui Wu et al. · Proceedings of the National Academy of Sciences · 2010 · 838 citations · Full text

, , +15

Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice

Cheng‐Liang Luo, B.-X. Li, Q.-Q. Li et al. · Neuroscience · 2011 · 194 citations

, , +14

Hydrogen Sulfide Ameliorates Homocysteine-Induced Alzheimer’s Disease-Like Pathology, Blood–Brain Barrier Disruption, and Synaptic Disorder

Pradip K. Kamat, Philip Kyles, Anuradha Kalani et al. · Molecular Neurobiology · 2015 · 167 citations

, , +16

Hydrogen Sulfide Offers Neuroprotection on Traumatic Brain Injury in Parallel with Reduced Apoptosis and Autophagy in Mice

Mingyang Zhang, Haiyan Shan, Pan Chang et al. · PLoS ONE · 2014 · 123 citations · Full text

, , +17

Baicalin provides neuroprotection in traumatic brain injury mice model through Akt/Nrf2 pathway

Jian Zhou, Wei Dai, Yihao Zhu et al. · Drug Design Development and Therapy · 2018 · 105 citations · Full text

, , +15