Concepedia

ONX0912, a selective oral proteasome inhibitor, triggering mitochondrial apoptosis and mitophagy in liver cancer

Mengmeng Wu, Ping Chen, Fuchen Liu, Bin Lv, Mengxiao Ge, Peicheng Jiang, Wei Xu, Xiuping Liu, Dongqin Yang

Biochemical and Biophysical Research Communications · 2021 · 12 citations · 9 references

DOI

Concepts

References

9

A novel orally active proteasome inhibitor ONX 0912 triggers in vitro and in vivo cytotoxicity in multiple myeloma

Dharminder Chauhan, Ajita Singh, Monette Aujay et al. · Blood · 2010 · 217 citations · Full text

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The immunoproteasome: a novel drug target for autoimmune diseases.

Michael Basler, Sarah Mundt, Annegret Bitzer et al. · PubMed · 2015 · 124 citations

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Carfilzomib and ONX 0912 Inhibit Cell Survival and Tumor Growth of Head and Neck Cancer and Their Activities Are Enhanced by Suppression of Mcl-1 or Autophagy

Yan Zang, Sufi M. Thomas, Elena T. Chan et al. · Clinical Cancer Research · 2012 · 79 citations

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Selective inhibition of chymotrypsin-like activity of the immunoproteasome and constitutive proteasome in Waldenström macroglobulinemia

Aldo M. Roccaro, Antonio Sacco, Monette Aujay et al. · Blood · 2010 · 78 citations · Full text

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PSMB8 and PBK as potential gastric cancer subtype-specific biomarkers associated with prognosis

Chae Hwa Kwon, Hye Ji Park, Yu Ri Choi et al. · Oncotarget · 2016 · 71 citations · Full text

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