Concepedia

H2O2 enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage

Jianqiang Chen, Xiangxiang Jin, Zhe Shen, Yanan Mei, Jufan Zhu, Xiaodan Zhang, Guang Liang, Xiaohui Zheng

Medical Oncology · 2021 · 14 citations · 19 references

DOI

Concepts

References

19

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

Ting‐Chao Chou · Cancer Research · 2010 · 5.7K citations

, , +15

Production of large amounts of hydrogen peroxide by human tumor cells.

Ted P. Szatrowski, Carl Nathan · PubMed · 1991 · 2.5K citations

, , +17

The comet assay: a method to measure DNA damage in individual cells

Peggy L. Olive, Judit P. Banáth · Nature Protocols · 2006 · 1.8K citations

, , +14

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

Frank Weinberg, Robert B. Hamanaka, William W. Wheaton et al. · Proceedings of the National Academy of Sciences · 2010 · 1.7K citations

, , +17

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

Kui Lei, Roger J. Davis · Proceedings of the National Academy of Sciences · 2003 · 1.1K citations · Full text

, , +16