Ginsenoside-Rg1 acts as an IDO1 inhibitor, protects against liver fibrosis via alleviating IDO1-mediated the inhibition of DCs maturation

LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis

Meng Xu, Honghai Xu, Lin Yuan et al. · Cell · 2019 · 221 citations · Full text

Medicine, Molecular Biology, Pathology +9

IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis

Kumar S. Bishnupuri, David M. Alvarado, Alexander N. Khouri et al. · Cancer Research · 2019 · 202 citations

Medicine, Cancer Biology, Oncology +15

miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy

Qian Huang, Jiajia Xia, Lei Wang et al. · Journal of Hematology & Oncology · 2018 · 134 citations · Full text

Life Sciences, Immunology, Oncology +17

Physalin D attenuates hepatic stellate cell activation and liver fibrosis by blocking TGF-β/Smad and YAP signaling

Dejuan Xiang, Jie Zou, Xiaoyun Zhu et al. · Phytomedicine · 2020 · 114 citations

Life Sciences, Biochemistry, Molecular Biology +14

Ginsenoside Rg1 Protects against Non-alcoholic Fatty Liver Disease by Ameliorating Lipid Peroxidation, Endoplasmic Reticulum Stress, and Inflammasome Activation

Yashu Xu, Cheng Yang, Shujun Zhang et al. · Biological and Pharmaceutical Bulletin · 2018 · 97 citations · Full text

Life Sciences, Nutritional Sciences, Pharmacology +17