A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

Heather P. Harding, Yuhong Zhang, David Ron · Nature · 1999 · 3.2K citations

Protein Function, Signal Transduction, Protein Folding +6

OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion

Christian Frezza, Sara Cipolat, Olga Martins de Brito et al. · Cell · 2006 · 1.6K citations · Full text

Signal Transduction, Mitochondrial Function, Medicine +3

Brown adipose tissue activity controls triglyceride clearance

Alexander Bartelt, Oliver T. Bruns†, Rudolph Reimer et al. · Nature Medicine · 2011 · 1.6K citations

Obesity, Metabolic Syndrome, Body Composition +7

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

Sara Cogliati, Christian Frezza, María Eugenia Soriano et al. · Cell · 2013 · 1.2K citations · Full text

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

Sara B. Cullinan, Donna Zhang, Mark Hannink et al. · Molecular and Cellular Biology · 2003 · 1.2K citations · Full text

Apoptosis, Nrf2 Transcription Factor, Cell Death +16