Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain

Esther Lapuente-Brun, Raquel Moreno‐Loshuertos, Rebeca Acín‐Pérez, +15

Science

Biophysical ModelingMolecular BiologyMitochondrial BiologyMitochondrial BiogenesisProtein Folding +14

NDUFA4 Is a Subunit of Complex IV of the Mammalian Electron Transport Chain

Eduardo Balsa, Ricardo De Marco, Ester Perales‐Clemente, +4

Cell Metabolism

BiochemistryReactive Nitrogen SpecieNatural SciencesMolecular BiologyProtein Transport +3

Induction of the Mitochondrial NDUFA4L2 Protein by HIF-1α Decreases Oxygen Consumption by Inhibiting Complex I Activity

Daniel Tello, Eduardo Balsa, Bárbara Acosta‐Iborra, +12

Cell Metabolism

Redox SignalingBiochemistryMitochondrial FunctionMitochondrial DynamicPhysiology +7

ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis

Eduardo Balsa, Meghan S. Soustek, Ajith J. Thomas, +7

Molecular Cell

Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells

Liliana M. Sanmarco, Joseph M. Rone, Carolina Manganeli Polonio, +32

Nature

Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death

Eduardo Balsa, Elizabeth A. Perry, Christopher F. Bennett, +4

Nature Communications

A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation

Pedro Latorre‐Muro, Katherine E. O’Malley, Christopher F. Bennett, +6

Cell Metabolism

MitophagySignal TransductionCold-stress-inducible Perk/ogt AxisMitochondrial FunctionMedicine +9

Role of Mitochondrial Complex IV in Age-Dependent Obesity

Inés Soro-Arnáiz, Qilong Oscar Yang Li, Mar Torres‐Capelli, +18

Cell Reports

ObesityMetabolic SyndromeMitochondrial FunctionPhysiologyMitochondrial Complex Iv +3

Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations

Joeva J. Barrow, Eduardo Balsa, Francisco Verdeguer, +10

Molecular Cell

Mitochondrial MyopathyMitophagyMitochondrial BiogenesisMitochondrial FunctionGenetics +6

H3K27me3-mediated PGC1α gene silencing promotes melanoma invasion through WNT5A and YAP

Chi Luo, Eduardo Balsa, Elizabeth A. Perry, +5

Journal of Clinical Investigation

ImmunologyMalignant MelanomaPromotes Melanoma InvasionCancer BiologyTumor Biology +17