Molecular Therapy — Methods & Clinical Development · 2021 · 30 citations · 35 references
PharmacyBioengineeringBiomedical EngineeringDrug DeliveryGene DeliveryTissue EngineeringGene Delivery VectorsHydrogelsIn Vivo Gene DeliveryTissue TargetingVector DesignViral Vector-mediated TransgenesisAdeno-associated Viral VectorsAdenoviral VectorsEx Vivo DeliveryHydrogel Delivery SystemsHydrogel-based DeliveryHydrogel-based Delivery SystemsVascular TargetingViral Vector Delivery
into AAV9SLR-containing hydrogel, and efficient transduction could be confirmed. These findings demonstrate that alginate hydrogel harboring a vascular-targeting AAV9SLR vector allows efficient local transduction of the aortic wall.
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Stephen R. Russell, Jean Bennett, Jennifer Wellman et al. · The Lancet · 2017 · 1.9K citations
Multiyear Follow-up of AAV5-hFVIII-SQ Gene Therapy for Hemophilia A
John Pasi, Savita Rangarajan, Nina Mitchell et al. · New England Journal of Medicine · 2020 · 458 citations · Full text
Recombinant Gene Expression in Vivo Within Endothelial Cells of the Arterial Wall
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