Concepedia

Baeckein E suppressed NLRP3 inflammasome activation through inhibiting both the priming and assembly procedure: Implications for gout therapy

Xiaobing Lin, Hao Wang, Xiaofei An, Junhan Zhang, Jin Kuang, Ji-Qin Hou, Ming Yan

Phytomedicine · 2021 · 42 citations · 25 references

DOI

Concepts

References

25

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.5K citations

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A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.4K citations

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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

Wanting He, Haoqiang Wan, Lichen Hu et al. · Cell Research · 2015 · 2.5K citations · Full text

, , +16

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

Alvin Lu, Venkat Giri Magupalli, Jianbin Ruan et al. · Cell · 2014 · 1.3K citations

, , +10

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

Edward A. Miao, Irina A. Leaf, Piper M. Treuting et al. · Nature Immunology · 2010 · 1.3K citations · Full text

, , +16