Concepedia

Immunomodulatory activity of puerarin in RAW264.7 macrophages and cyclophosphamide-induced immunosuppression mice

Yuexing Chang, Ailing Guo, Yanlin Jing, Junjie Lin, Yuanyuan Sun, Lulu Kong, Haohang Zheng, Yun Deng

Immunopharmacology and Immunotoxicology · 2021 · 33 citations · 36 references

DOI

Abstract

Puerarin exhibited an upregulated immunomodulatory effect on RAW264.7 macrophages and immunosuppression mice. In addition, puerarin had a downregulated immunomodulatory effect on RAW264.7 macrophages. The results suggest that puerarin could be a promising immunomodulator to assist in the treatment of tumors.

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