In-situ Reverse Phased HPLC Analysis of Intact Antibody-Drug Conjugates

Development of potent monoclonal antibody auristatin conjugates for cancer therapy

Svetlana O. Doronina, Brian E. Toki, Michael Torgov et al. · Nature Biotechnology · 2003 · 1.2K citations

Pharmacy, Medicinal Chemistry, Oncology +14

The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma

Peter D. Senter, Eric L. Sievers · Nature Biotechnology · 2012 · 752 citations

Medicine, Oncology, Pharmacology +15

Brentuximab Vedotin (SGN-35)

Jessica Katz, John E. Janik, Anas Younes · Clinical Cancer Research · 2011 · 363 citations

Medicine, Oncology, Pharmacology +16

Innovative Native MS Methodologies for Antibody Drug Conjugate Characterization: High Resolution Native MS and IM-MS for Average DAR and DAR Distribution Assessment

François Debaene, Amandine Bœuf, Elsa Wagner‐Rousset et al. · Analytical Chemistry · 2014 · 173 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Polatuzumab vedotin in combination with immunochemotherapy in patients with previously untreated diffuse large B-cell lymphoma: an open-label, non-randomised, phase 1b–2 study

Hervé Tilly, Franck Morschhauser, Nancy L. Bartlett et al. · The Lancet Oncology · 2019 · 139 citations · Full text

Medicine, Immunology, Oncology +9