Quercetin relaxes human gastric smooth muscles directly through ATP‐sensitive potassium channels and not depending on the nitric oxide pathway

Beata Modzelewska, Krzysztof Drygalski, Tomasz Kleszczewski, Andrzej Chomentowski, Krzysztof Koryciński, Aleksandra Kiełczewska, Patrycja Pawłuszewicz, Hady Razak Hady

Neurogastroenterology & Motility · 2021 · 22 citations · 33 references

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Abstract

In conclusion, the current study was the first to show that quercetin-induced relaxation of human gastric smooth muscle occurs directly through K<sup>+</sup><sub>ATP</sub> channels and independently to NO pathways. The present results suggest that quercetin is a potential nutraceutical in the treatment of functional gastrointestinal dyspepsia and other minor gastric muscle motility disturbance.

References

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