Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Richard Palmer, Anthony G. Ferrige, Salvador Moncada · Nature · 1987 · 10.8K citations

Veterinary Medicine, Cell Biology, Physiology +10

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

L J Ignarro, Georgette M. Buga, K S Wood et al. · Proceedings of the National Academy of Sciences · 1987 · 5.1K citations · Full text

Medicine, Pharmacology, Physiology +12

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

John Garthwaite, Sarah L. Charles, Russ Chess‐Williams · Nature · 1988 · 2.6K citations

Life Sciences, Neurobiology, Neuroscience +13

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

Ryszard J. Gryglewski, Richard Palmer, Salvador Moncada · Nature · 1986 · 2.4K citations

Life Sciences, Cell Biology, Physiology +13

Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.

Richard G. Knowles, Richard Palmer, Salvador Moncada · Proceedings of the National Academy of Sciences · 1989 · 1.4K citations · Full text

Life Sciences, Biochemistry, Neurobiology +13