Proliferative polyploid cells give rise to tumors via ploidy reduction

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations

Knockout Mouse, Spontaneous Tumours, Medicine +9

A global double‐fluorescent Cre reporter mouse

Mandar D. Muzumdar, Bosiljka Tasic, Kazunari Miyamichi et al. · genesis · 2007 · 3.6K citations · Full text

‘Green mice’ as a source of ubiquitous green cells

Masaru Okabe, Masahito Ikawa, Katsuya Kominami et al. · FEBS Letters · 1997 · 2.6K citations

Biology, Xenotransplantation, Bioluminescence +13

Easy quantitative assessment of genome editing by sequence trace decomposition

Eva K. Brinkman, Tao Chen, Mario Amendola et al. · Nucleic Acids Research · 2014 · 2.5K citations · Full text

Engineering, Genetics, Molecular Biology +19

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

Randall J. Platt, Sidi Chen, Yang Zhou et al. · Cell · 2014 · 2K citations · Full text

Genetic Engineering, Genome Engineering, Gene Editing +4