Dysregulated miRNAs contribute to altered placental glucose metabolism in patients with gestational diabetes via targeting GLUT1 and HK2

Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme

Amparo Wolf, Sameer Agnihotri, Johann Micallef et al. · The Journal of Experimental Medicine · 2011 · 798 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Cell-type-specific signatures of microRNAs on target mRNA expression

Pranidhi Sood, Azra Krek, Mihaela Zavolan et al. · Proceedings of the National Academy of Sciences · 2006 · 645 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

Dannielle C. DeWaal, Véronique Nogueira, Alexander R. Terry et al. · Nature Communications · 2018 · 558 citations · Full text

Medicine, Cancer Biology, Oncology +17

Increased Risk of Cardiovascular Disease in Young Women Following Gestational Diabetes Mellitus

Baiju R. Shah, Ravi Retnakaran, Gillian L. Booth · Diabetes Care · 2008 · 487 citations · Full text

Medicine, Gynecology, Obstetrics +17

A novel miR‐155/miR‐143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells

Shuai Jiang, Ling-Fei Zhang, Hong-Wei Zhang et al. · The EMBO Journal · 2012 · 363 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +16