Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities

Random Forests

Leo Breiman · Machine Learning · 2001 · 126.2K citations · Full text

HTSeq—a Python framework to work with high-throughput sequencing data

Simon Anders, Paul Theodor Pyl, Wolfgang Huber · Bioinformatics · 2014 · 22.7K citations · Full text

Life Sciences, Bioinformatics, Biology +11

Adjusting batch effects in microarray expression data using empirical Bayes methods

W. Evan Johnson, Cheng Li, Ariel Rabinovic · Biostatistics · 2006 · 9.1K citations · Full text

Life Sciences, Bioinformatics, Biostatistics +12

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Roel G.W. Verhaak, Katherine A. Hoadley, Elizabeth Purdom et al. · Cancer Cell · 2010 · 7.7K citations · Full text

Medicine, Molecular Genetics, Oncology +12

TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data

Antonio Colaprico, Tiago C. Silva, Catharina Olsen et al. · Nucleic Acids Research · 2015 · 4.5K citations · Full text

Life Sciences, Bioinformatics, Oncology +17