Treatment with a triazole inhibitor of the mitochondrial permeability transition pore fully corrects the pathology of sapje zebrafish lacking dystrophin

Dystrophin: The protein product of the duchenne muscular dystrophy locus

Eric P. Hoffman, Robert H. Brown, Louis M. Kunkel · Cell · 1987 · 4.7K citations

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Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs

James A. Gagnon, Eivind Valen, Summer B. Thyme et al. · PLoS ONE · 2014 · 996 citations · Full text

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Opening of the Mitochondrial Permeability Transition Pore Causes Depletion of Mitochondrial and Cytosolic NAD+and Is a Causative Event in the Death of Myocytes in Postischemic Reperfusion of the Heart

Fabio Di Lisa, Roberta Menabò, Marcella Canton et al. · Journal of Biological Chemistry · 2001 · 679 citations · Full text

Life Sciences, Biochemistry, Physiology +17

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

Andrew M. Bellinger, Steve Reiken, Christian Carlson et al. · Nature Medicine · 2009 · 519 citations · Full text

Life Sciences, Biochemistry, Physiology +14

Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency

William Irwin, Natascha Bergamin, Patrizia Sabatelli et al. · Nature Genetics · 2003 · 508 citations

Life Sciences, Cell Biology, Pathology +15