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Prolonged cultured human hepatocytes as an in vitro experimental system for the evaluation of potency and duration of activity of RNA therapeutics: Demonstration of prolonged duration of gene silencing effects of a GalNAc-conjugated human hypoxanthine phosphoribosyl transferase (HPRT1) siRNA

Rna TherapeuticsHepatologyProlonged DurationLiver PhysiologyMedicineNatural SciencesHepatitisCultured Human HepatocytesHepatotoxicityAntisense TherapyLiverPharmacologyCell BiologyGene ExpressionHepatocellular CarcinomaDrug-induced Liver Injury