Sara C. Humphreys - Concepedia

Author

Sara C. Humphreys

Amgen (United States)ORCID

Also Known As

S. C. Humphreys, Sara C Humphreys, Sara C. Humphreys, Sara Humphreys

Publications

470

Citations

H-Index

Concepts

All Affiliations

Amgen (United States)Washington State University

About

Sara C. Humphreys is an author at Amgen (United States) specializing in medicine, cell biology, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	121
2	Engineering	2	2	51
3	Natural Sciences	2	2	90
4	Biochemistry	2	2	40
5	Biomolecular Engineering	2	2	51

Sara C. Humphreys

Publications

283

Citations

H-Index

Page 1

	Year	Citations
Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs Nan Bai, Kristin M. Riching, Aman Makaju, Journal of Biological Chemistry Protein AssemblyMolecular BiologyTarget Protein UbiquitinationUbiquitin-proteasome SystemProtein Expression	2022	78
The two faces of aldehyde oxidase: Oxidative and reductive transformations of 5-nitroquinoline Erickson M. Paragas, Sara C. Humphreys, Joshua Min, Biochemical Pharmacology EngineeringAldehyde DehydrogenaseBiochemistryReactive Nitrogen SpecieAldehyde Oxidase	2017	30
Emerging siRNA Design Principles and Consequences for Biotransformation and Disposition in Drug Development Sara C. Humphreys, Mai B. Thayer, Jabbar Campbell, Journal of Medicinal Chemistry	2020	26
Plasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNA Sara C. Humphreys, Mai B. Thayer, Julie M. Lade, Drug Metabolism and Disposition	2019	24
POE Immunoassay: Plate-based oligonucleotide electro-chemiluminescent immunoassay for the quantification of nucleic acids in biological matrices Mai B. Thayer, Sara C. Humphreys, Kyu Chung, Scientific Reports	2020	24
Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies Marissa Mock, Alex W. Jacobitz, Christopher J. Langmead, mAbs	2023	24
Introducing an In Vitro Liver Stability Assay Capable of Predicting the In Vivo Pharmacodynamic Efficacy of siRNAs for IVIVC Babak Basiri, Fang Xie, Bin Wu, Molecular Therapy — Nucleic Acids	2020	23
Quantification of siRNA-Antibody Conjugates in Biological Matrices by Triplex-Forming Oligonucleotide ELISA Sara C. Humphreys, Mai B. Thayer, Iain D. G. Campuzano, Nucleic Acid Therapeutics EngineeringImmunologyMolecular BiologyGene DeliveryTherapeutics	2019	21
Prolonged cultured human hepatocytes as an in vitro experimental system for the evaluation of potency and duration of activity of RNA therapeutics: Demonstration of prolonged duration of gene silencing effects of a GalNAc-conjugated human hypoxanthine phosphoribosyl transferase (HPRT1) siRNA Qian Yang, Sara C. Humphreys, Julie M. Lade, Biochemical Pharmacology Rna TherapeuticsHepatologyProlonged DurationLiver PhysiologyMedicine	2020	12
ecoAO: A Simple System for the Study of Human Aldehyde Oxidases Role in Drug Metabolism Erickson M. Paragas, Sara C. Humphreys, Joshua Min, ACS Omega	2017	11

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