Cold storage of platelets in <scp>platelet additive solution</scp> maintains mitochondrial integrity by limiting initiation of apoptosis‐mediated pathways

Abstract

Mitochondrial function and molecular analyses defined CSP priming as distinctly different from the well-documented RTP storage lesion. While current blood bank storage at room temperature is limited to 5 to 7 days, refrigeration and storage in PAS for up to 15 days may represent an opportunity to enhance inventories and access to PLT hemostatic support for bleeding patients.