Synergistic Antifungal Effect of Fluconazole Combined with ZnO Nanoparticles against Candida albicans Strains from Vaginal Candidiasis

Abstract

Background and Objective: The prevalence of the infections caused by Candida species has led to a significant increase in their resistance to antifungal compounds. The aim of this study was to i) investigate drug resistance ii) evaluate the incidence of Candida albicans drug resistance pattern in the vaginal samples of women referring to health centers of Qom province, and iii) examine the effect of Zn nanoparticles combined with fluconazole against C. albicans isolates.