Concepedia

Propofol reduces renal ischemia/reperfusion-induced acute lung injury by stimulating sirtuin 1 and inhibiting pyroptosis

Zhaohui Liu, Yanli Meng, Yu Rebecca Miao, Lili Yu, Qiannan Yu

Aging · 2020 · 43 citations · 24 references

DOIFull text

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Concepts

Abstract

in rat alveolar macrophages incubated with serum from the rI/R rat model. These findings indicate that propofol attenuates rI/R-induced ALI by suppressing pyroptosis, possibly by upregulating SIRT1 in the lungs.

References

24

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Tao‐Tao Tang, Lin‐Li Lv, Mingming Pan et al. · Cell Death and Disease · 2018 · 211 citations · Full text

, , +17

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Francesco Imperatore, Julien Maurizio, Stephanie Vargas Aguilar et al. · The EMBO Journal · 2017 · 132 citations · Full text

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Intraoperative Modulation of Alveolar Macrophage Function during Isoflurane and Propofol Anesthesia 

Naoki Kotani, Hiroshi Hashimoto, Daniel I. Sessler et al. · Anesthesiology · 1998 · 125 citations

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