Concepedia

Murine double minute 2 inhibition alone or with cytarabine in acute myeloid leukemia: Results from an idasanutlin phase 1/1b study⋆

Karen Yee, Cristina Papayannidis, Norbert Vey, Michael Dickinson, Kevin R. Kelly, Sarit Assouline, Margaret Kasner, Karen Seiter, Mark W. Drummond, Sung‐Soo Yoon,

Leukemia Research · 2020 · 47 citations · 16 references

DOI

Concepts

References

16

Understanding the function–structure and function–mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

Shunsuke Kato, Shuang-Yin Han, Wen Liu et al. · Proceedings of the National Academy of Sciences · 2003 · 901 citations · Full text

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SAR405838: An Optimized Inhibitor of MDM2–p53 Interaction That Induces Complete and Durable Tumor Regression

Shaomeng Wang, Wei Sun, Yujun Zhao et al. · Cancer Research · 2014 · 338 citations · Full text

, , +8

A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation

Eran Kotler, Odem Shani, Guy Goldfeld et al. · Molecular Cell · 2018 · 302 citations · Full text

, , +14

The human MDM-2 oncogene is overexpressed in leukemias

CE Bueso-Ramos, Yun Yang, E deLeon et al. · Blood · 1993 · 258 citations · Full text

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The human MDM-2 oncogene is overexpressed in leukemias

CE Bueso-Ramos, Yun Yang, E deLeon et al. · Blood · 1993 · 250 citations · Full text

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