Synergistic antidepressant- and anxiolytic-like effects of harmaline along with cinanserin in acute restraint stress-treated mice

Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex

Shuichi Chiba, Tadahiro Numakawa, Midori Ninomiya et al. · Progress in Neuro-Psychopharmacology and Biological Psychiatry · 2012 · 674 citations

Life Sciences, Neurobiology, Neuroscience +17

The therapeutic role of 5-HT1A and 5-HT2A receptors in depression.

Pau Celada, M. Victoria Puig, Mercè Amargós‐Bosch et al. · PubMed · 2004 · 493 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Depression and anxiety

John Tiller · The Medical Journal of Australia · 2013 · 405 citations

Pharmacy, Pharmacotherapy, Psychiatry +16

Prolonged Restraint Stress Increases IL-6, Reduces IL-10, and Causes Persistent Depressive-Like Behavior That Is Reversed by Recombinant IL-10

Jeffrey L. Voorhees, A.J. Tarr, Eric S. Wohleb et al. · PLoS ONE · 2013 · 237 citations · Full text

Life Sciences, Immunology, Neuroscience +17

The Effect of Paroxetine on 5-HT_2A Receptors in Depression: An [¹⁸F]Setoperone PET Imaging Study

Jeffrey H. Meyer, Shitij Kapur, Beata S. Eisfeld et al. · American Journal of Psychiatry · 2001 · 233 citations

Medicine, Pharmacology, Psychiatry +17