Concepedia

Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction

Ramya Tokala, Surbhi Mahajan, Gaddam Kiranmai, Dilep Kumar Sigalapalli, Sravani Sana, Stephy Elza John, Narayana Nagesh, Nagula Shankaraiah

Bioorganic Chemistry · 2020 · 51 citations · 47 references

DOI

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47

Cancer statistics, 2020

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2020 · 21.4K citations · Full text

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Lead- and drug-like compounds: the rule-of-five revolution

Christopher A. Lipinski · Drug Discovery Today Technologies · 2004 · 6.1K citations

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A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

I. Vermes, C. Haanen, H M Steffens-Nakken et al. · Journal of Immunological Methods · 1995 · 5.4K citations · Full text

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Cell Sensitivity Assays: The MTT Assay

Johan van Meerloo, Gertjan J.L. Kaspers, Jacqueline Cloos · Methods in molecular biology · 2011 · 2.5K citations

, , +9

A study of the interactions of some polypyridylruthenium(II) complexes with DNA using fluorescence spectroscopy, topoisomerisation and thermal denaturation

John M. Kelly, Alessandro Tossi, David J. McConnell et al. · Nucleic Acids Research · 1985 · 879 citations · Full text

, , +15