Concepedia

Publication | Open Access

Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma

DOIFull Paper Access

105

Citations

19

References

2020

Year

Runze Shang, Xinhua Song, Pan Wang, Yi Zhou, Xinjun Lu, Jingxiao Wang, Meng Xu, Xinyan Chen, Kirsten Utpatel, Li Che,
Gut

Abstract

c-MET/ERK/p21/PKM2 cascade and VEGFR2-induced angiogenesis are the primary targets of cabozantinib in HCC treatment. Combination therapies with cabozantinib and mTOR inhibitors may be effective against human HCC.

References

YearCitations

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