Concepedia

Publication | Open Access

<p>Tranilast Inhibits Pulmonary Fibrosis by Suppressing TGFβ/SMAD2 Pathway</p>

DOIFull Paper Access

24

Citations

35

References

2020

Year

Motoyasu Kato, Fumiyuki Takahashi, Tadashi Sato, Yoichiro Mitsuishi, Ken Tajima, Hiroaki Ihara, Fariz Nurwidya, Hario Baskoro, Akiko Murakami, Isao Kobayashi,
Drug Design Development and Therapy

Abstract

These findings suggest that tranilast inhibits pulmonary fibrosis by suppressing TGFβ/SMAD2-mediated ECM protein production, presenting tranilast as a promising and novel anti-fibrotic agent for the treatment of IPF.

References

YearCitations

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