Concepedia

Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors

Mamdouh F. A. Mohamed, Adel A. Marzouk, Ayman Nafady, Dalia A. Elgamal, Rasha M. Allam, Gamal El‐Din A. Abuo‐Rahma, Hussein I. El‐Subbagh, Amr H. Moustafa

Bioorganic Chemistry · 2020 · 53 citations · 43 references

DOI

Concepts

References

43

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

, , +15

Nitric oxide synthases: structure, function and inhibition

W. Alderton, Chris E. Cooper, Richard G. Knowles · Biochemical Journal · 2001 · 2.7K citations

, , +17

Inflammation 2010: New Adventures of an Old Flame

Ruslan Medzhitov · Cell · 2010 · 1.8K citations · Full text

, , +12

Essential Role of Induced Nitric Oxide in the Initiation of the Inflammatory Response after Hemorrhagic Shock

Christian Hierholzer, Brian G. Harbrecht, John M. Menezes et al. · The Journal of Experimental Medicine · 1998 · 473 citations · Full text

, , +17

A New Atom-Additive Method for Calculating Partition Coefficients

Renxiao Wang, Ying Fu, Luhua Lai · Journal of Chemical Information and Computer Sciences · 1997 · 428 citations

, , +16