Concepedia

Synthesis and structure-activity relationship of coumarins as potent Mcl-1 inhibitors for cancer treatment

Yangliu Xia, Jingjing Wang, Shi-Yang Li, Yong Liu, Frank J. Gonzalez, Ping Wang, Guang‐Bo Ge

Bioorganic & Medicinal Chemistry · 2020 · 30 citations · 38 references

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References

38

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

Mark F. van Delft, Andrew H. Wei, Kylie D. Mason et al. · Cancer Cell · 2006 · 1.2K citations · Full text

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The maximal affinity of ligands

Irwin D. Kuntz, K. Chen, Kim A. Sharp et al. · Proceedings of the National Academy of Sciences · 1999 · 845 citations

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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

Ingrid E. Wertz, Saritha Kusam, Cynthia Lam et al. · Nature · 2011 · 810 citations

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Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-xL is an essential survival protein of human myeloma cells

Sophie Derenne, Brett P. Monia, Nicholas M. Dean et al. · Blood · 2002 · 430 citations · Full text

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Anticancer activity of new coumarin substituted hydrazide–hydrazone derivatives

Tamer Nasr, Samir Bondock, Mаhmoud Youns · European Journal of Medicinal Chemistry · 2014 · 329 citations

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