Concepedia

Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos

Michael V. Zuccaro, Jia Xu, Carl A. Mitchell, Diego Marín, Raymond Zimmerman, Bhavini Rana, Everett Weinstein, Rebeca T. King, Katherine L. Palmerola, Morgan Elizabeth Smith,

Cell · 2020 · 323 citations · 33 references

DOIFull text

Open access

Concepts

References

33

Search-and-replace genome editing without double-strand breaks or donor DNA

Andrew V. Anzalone, Peyton B. Randolph, Jessie R. Davis et al. · Nature · 2019 · 4.7K citations · Full text

, , +9

Telomerase activity in human germline and embryonic tissues and cells

Woodring E. Wright, Mieczyslaw A. Piatyszek, William E. Rainey et al. · Developmental Genetics · 1996 · 1.4K citations

, , +16

CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

Puping Liang, Yanwen Xu, Xiya Zhang et al. · Protein & Cell · 2015 · 1.1K citations · Full text

, , +13

Correction of a pathogenic gene mutation in human embryos

Hong Ma, Nuria Martí‐Gutiérrez, Sang-Wook Park et al. · Nature · 2017 · 951 citations

, , +12

Chromosome instability is common in human cleavage-stage embryos

Evelyne Vanneste, Thierry Voet, Cédric Le Caignec et al. · Nature Medicine · 2009 · 899 citations

, , +14