Publication | Open Access
The 3.2-Å resolution structure of human mTORC2
96
Citations
55
References
2020
Year
Molecular PharmacologyMolecular PhysiologySignal TransductionBiochemistryNatural SciencesMechanism Of ActionMolecular BiologyReceptor (Biochemistry)Biochemical InteractionBiomolecular InteractionMtorc2 StabilityMtorc2 RevealsChemical BiologyMedicineHuman Mtorc2Cellular PhysiologyDrug DiscoveryRapamycin Insensitivity
The structure of mTORC2 reveals the basis of its rapamycin insensitivity and explains how mTORC2 stability controls activity.
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