Altered chromatin landscape in circulating T follicular helper and regulatory cells following grass pollen subcutaneous and sublingual immunotherapy

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

Jason D. Buenrostro, Paul G. Giresi, Lisa C. Zaba et al. · Nature Methods · 2013 · 7K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

M. Ryan Corces, Alexandro E. Trevino, Emily G. Hamilton et al. · Nature Methods · 2017 · 2.8K citations

Life Sciences, Bioinformatics, Molecular Biology +15

FlowSOM: Using self‐organizing maps for visualization and interpretation of cytometry data

Sofie Van Gassen, Britt Callebaut, Mary J. van Helden et al. · Cytometry Part A · 2015 · 2.1K citations

Computing, Cell Biology, Visualization +12

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

El-ad David Amir, Kara L. Davis, Michelle D. Tadmor et al. · Nature Biotechnology · 2013 · 1.6K citations · Full text

Life Sciences, Cancer Biology, Cell Biology +12

Bcl6 Mediates the Development of T Follicular Helper Cells

Roza Nurieva, Yeonseok Chung, Gustavo Martínez et al. · Science · 2009 · 1.5K citations · Full text

Life Sciences, Developmental Biology, Immunology +17