An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

M. Ryan Corces, Alexandro E. Trevino, Emily G. Hamilton, +19

Nature Methods

EngineeringFrozen TissuesBiosignal ProcessingBiomedical ImagingBiomedical Analysis +3

Integrating genomic features for non-invasive early lung cancer detection

Jacob J. Chabon, Emily G. Hamilton, David M. Kurtz, +45

Nature

EngineeringCancer DetectionGenomic FeaturesMedicineMultiple Pulmonary Nodule +6

Noninvasive Early Identification of Therapeutic Benefit from Immune Checkpoint Inhibition

Barzin Y. Nabet, Mohammad Shahrokh Esfahani, Everett J. Moding, +29

Cell

Immune EvasionAutoimmune DiseaseAllergyImmunologyTumor Immunity +9

Enhanced detection of minimal residual disease by targeted sequencing of phased variants in circulating tumor DNA

David M. Kurtz, Joanne Soo, Lyron Co Ting Keh, +26

Nature Biotechnology

OncologyEnhanced DetectionSomatic VariantTumor HeterogeneityMedicine +9

Convergence of placenta biology and genetic risk for schizophrenia

Gianluca Ursini, Giovanna Punzi, Qiang Chen, +20

Nature Medicine

PsychiatryGeneticsPsychiatric GeneticsSchizophreniaMaternal Health +5

DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors

Tali Mazor, Aleksandr Pankov, Brett Johnson, +18

Cancer Cell

Neuro-oncologyChromatinDevelopmental BiologySomatic VariantTumor Heterogeneity +9

Circulating Tumor DNA Analysis for Detection of Minimal Residual Disease After Chemoradiotherapy for Localized Esophageal Cancer

Tej D. Azad, Aadel A. Chaudhuri, Penny Fang, +18

Gastroenterology

Tumor Dna AnalysisEsophageal CancerCancer DetectionMedicinePathology +7

Inferring gene expression from cell-free DNA fragmentation profiles

Mohammad Shahrokh Esfahani, Emily G. Hamilton, Mahya Mehrmohamadi, +25

Nature Biotechnology

Functional GenomicsNatural SciencesGene RecognitionDna AnalysisDna Replication +6

<i>KEAP1/NFE2L2</i> Mutations Predict Lung Cancer Radiation Resistance That Can Be Targeted by Glutaminase Inhibition

Michael S. Binkley, Young-Jun Jeon, Monica Nesselbush, +28

Cancer Discovery

Polybrominated diphenyl ethers (PBDEs) and hydroxylated PBDE metabolites (OH-PBDEs) in maternal and fetal tissues, and associations with fetal cytochrome P450 gene expression

Ami R. Zota, Susanna D. Mitro, Joshua F. Robinson, +5

Environment International

BiochemistryMedicineDevelopmental ToxicologyForensic ToxicologyMaternal Health +7