Concepedia

Tanshinone IIA prevents LPS-induced inflammatory responses in mice via inactivation of succinate dehydrogenase in macrophages

Qiu‐Yan Liu, Yu Zhuang, Xianrui Song, Qun Niu, Qiushuang Sun, Xiaonan Li, Ning Li, Baolin Liu, Fang Huang, Zhixia Qiu

Acta Pharmacologica Sinica · 2020 · 62 citations · 23 references

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References

23

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

Peter J. Murray, Judith E. Allen, Subhra K. Biswas et al. · Immunity · 2014 · 6.2K citations · Full text

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A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.4K citations

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Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik et al. · Nature · 2013 · 4K citations · Full text

, , +12

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Evanna L. Mills, Beth Kelly, Angela Logan et al. · Cell · 2016 · 2.2K citations · Full text

, , +14

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase

Mary Selak, Sean M. Armour, Elaine D. MacKenzie et al. · Cancer Cell · 2005 · 2.1K citations · Full text

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