Intrathecal Injection of SIRT1-modified Human Mesenchymal Stem Cells Alleviates Neuropathic Pain in Rat

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

Gary J. Bennett, Yuanyu Xie · Pain · 1988 · 5.4K citations

Medicine, Neurobiology, Neurological Surgery +17

SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

Philipp Oberdoerffer, Shaday Michán, Michael McVay et al. · Cell · 2008 · 839 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines

Yonggang Sha, Jaroslaw W. Zmijewski, Zhiwei Xu et al. · The Journal of Immunology · 2008 · 391 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity

Hongying Yang, Wei Zhang, Heng Pan et al. · PLoS ONE · 2012 · 373 citations · Full text

Life Sciences, Cell Biology, Immunology +16

SIRT1 Deacetylates the DNA Methyltransferase 1 (DNMT1) Protein and Alters Its Activities

Lirong Peng, Zhigang Yuan, Hongbo Ling et al. · Molecular and Cellular Biology · 2011 · 226 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15