Early-onset renal cell carcinoma in PTEN harmatoma tumour syndrome

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

Sue Richards, Nazneen Aziz, Sherri J. Bale et al. · Genetics in Medicine · 2015 · 30.5K citations · Full text

Allelic Variant, Sequence Variants, Medicine +11

The National Comprehensive Cancer Network

William T. McGivney · Cancer · 1998 · 16.9K citations

Cancer Management, Pathology, Cancer Registration +17

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

Danny Liaw, Deborah J. Marsh, Jing Li et al. · Nature Genetics · 1997 · 2.1K citations

Thyroid Cancer Syndrome, Genetics, Pathology +4

Lifetime Cancer Risks in Individuals with Germline<i>PTEN</i>Mutations

Min-Han Tan, Jessica L. Mester, Joanne Ngeow et al. · Clinical Cancer Research · 2012 · 861 citations · Full text

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

Hong Sun, Ralf Lesche, Daming Li et al. · Proceedings of the National Academy of Sciences · 1999 · 816 citations · Full text

Phosphatidylinositol 3,4,5, Cell Death, Cell Proliferation +21