Resveratrol prevents TNF-<b>α</b>-induced VCAM-1 and ICAM-1 upregulation in endothelial progenitor cells via reduction of NF-<b>κ</b>B activation

Abstract

These findings provide new insights into RSV's anti-inflammatory and anti-atherosclerotic effects. RSV's mechanism of action might involve downregulation of VCAM-1, ICAM-1 and E-selectin by partial blockade of TNF-α-induced NF-κB activation and IκB-α phosphorylation in EPCs.