OncoImmunology · 2020 · 56 citations · 41 references
MedicineImmunologyOncologyCancer ImmunologyImmunotherapyTumor ImmunologyAntitumor T Cell ResponsesCancer ImmunotherapyCheckpoint Inhibitor TherapyImmune Checkpoint InhibitorsImmune Checkpoint RegulationT Cell Responses To TumorsAdaptive Antitumor ImmunityCd8 T Cell ActivationCd8+ Tumor-infiltrating LymphocytesCheckpoint Inhibitor AntibodiesCheckpoint Inhibitor SynergyImmune Checkpoint Inhibitor TherapySyngeneic Tumor ModelsTransforming Growth Factor Beta-mediated Immune Suppression
T cell responses. Together, these data support the hypothesis that TGFβ neutralization using SAR439459 synergizes with PD-1 blockade to promote antitumor immunity and formed the basis for the ongoing clinical investigation of SAR439459 in patients with cancer (NCT03192345).
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Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer
H. Borghaei, L. Paz-Ares, Leora Horn et al. · New England Journal of Medicine · 2015 · 9.5K citations · Full text
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
Evan Z. Macosko, Anindita Basu, Rahul Satija et al. · Cell · 2015 · 7.8K citations · Full text
The Immune Landscape of Cancer
Vésteinn Thórsson, David L. Gibbs, Scott D. Brown et al. · Immunity · 2018 · 6.2K citations · Full text
Medicine, Immunology, Oncology +17