Conservation and Rewiring of Functional Modules Revealed by an Epistasis Map in Fission Yeast

Assen Roguev, Sourav Bandyopadhyay, Martin Zofall, +13

Science

GeneticsEpistasis MapGenomic MechanismMolecular BiologyMolecular Genetics +20

Reactivation of Latent HIV-1 by Inhibition of BRD4

Jian Zhu, Gaurav D. Gaiha, Sinu P. John, +7

Cell Reports

Human RetrovirusImmunologyAntiviral ResponseMolecular BiologyVirology +5

Modulation of Cellular Disulfide-Bond Formation and the ER Redox Environment by Feedback Regulation of Ero1

Carolyn S. Sevier, Hongjing Qu, Nimrod Heldman, +3

Cell

Reductive StressFeedback RegulationSignal TransductionBiochemistryRedox Regulator +10

Systematic identification of synergistic drug pairs targeting HIV

Xu Tan, Long Hu, Lovelace J. Luquette, +7

Nature Biotechnology

Systematic IdentificationDrug TargetMedicineHuman RetrovirusHiv +2

Dynamic Behaviors of Lipid-Like Self-Assembling Peptide A<SUB>6</SUB>D and A<SUB>6</SUB>K Nanotubes

Aki Nagai, Yusuke Nagai, Hongjing Qu, +1

Journal of Nanoscience and Nanotechnology

Supramolecular AssemblyDynamic BehaviorsEngineeringBiochemistryPeptide Engineering +11

Comprehensive Identification of Host Modulators of HIV-1 Replication using Multiple Orthologous RNAi Reagents

Jian Zhu, Teresa Davoli, Jill M. Perriera, +15

Cell Reports

Pan-TGFβ inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade

Rita Greco, Hongjing Qu, Hui Qu, +16

OncoImmunology

BND-22, a first-in-class humanized ILT2-blocking antibody, promotes antitumor immunity and tumor regression

Ilana Mandel, Dana Haves Ziv, Ilana Goldshtein, +14

Journal for ImmunoTherapy of Cancer

Tiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy

Xu Tan, Zhi John Lu, Geng Gao, +8

Proceedings of the National Academy of Sciences

Viral ReplicationGeneticsSecondary StructureImmunologyMolecular Biology +19

Selective Adsorption of Pb2+ in the Presence of Mg2+ by Layer-by-Layer Self-Assembled MnO2/Mxene Composite Films

Hongjing Qu, Jiayan Deng, Dan Peng, +3

Processes

Environmental ElectrochemistryEngineeringMxene NanosheetsChemistryMineral Processing +18