Concepedia

Calcium signaling consequences of RyR2 mutations associated with CPVT1 introduced via CRISPR/Cas9 gene editing in human-induced pluripotent stem cell–derived cardiomyocytes: Comparison of RyR2-R420Q, F2483I, and Q4201R

Xiaohua Zhang, Hua Wei, Yanli Xia, Martin Morad

Heart Rhythm · 2020 · 28 citations · 27 references

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References

27

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell · 2007 · 20.2K citations

, , +12

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

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Mutations in the Cardiac Ryanodine Receptor Gene ( <i>hRyR2</i> ) Underlie Catecholaminergic Polymorphic Ventricular Tachycardia

Silvia G. Priori, Carlo Napolitano, Natascia Tiso et al. · Circulation · 2001 · 1.4K citations · Full text

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FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death

Xander H.T. Wehrens, Stephan E. Lehnart, Fannie Huang et al. · Cell · 2003 · 755 citations · Full text

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Regulation of Calcium Release Is Gated by Calcium Current, Not Gating Charge, in Cardiac Myocytes

Michael Näbauer, Geert Callewaert, Lars Nilausen Cleemann et al. · Science · 1989 · 453 citations

, , +17