Cureus · 2020 · 19 citations · 7 references
MedicineInternal MedicineSurgeryEndocrine SurgeryHepatologyTransplant SurgeryAcute Liver FailureLiver DiseaseLiver TransplantationSurgical Management Of HyperthyroidismThyroid DisordersThyroid SurgeryAcute Liver Failure ManagementAcute Liver Failure TreatmentDifferential Diagnosis CriteriaDifferential Diagnosis Of ThyrotoxicosisGraves' Disease TreatmentLiver Transplantation ManagementSurvival RatesThyroid Storm Management
Although mild elevations in liver enzymes are relatively common in thyrotoxicosis, acute liver failure (ALF) is an infrequent occurrence. Despite the emergence of liver transplantation as a viable treatment for ALF, survival rates continue to remain unsatisfactory, coupled with higher rates of postoperative complications and re-transplantation in this group. We present the disease course, management, and outcome of a patient with Graves' disease who presented with ALF secondary to thyroid storm. Thyrotoxicosis should always be included in the differential diagnosis of ALF, as timely diagnosis and management are crucial in achieving survival.
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Severe hyperthyroidism induces mitochondria-mediated apoptosis in rat liver
Geeta Upadhyay, Rajesh Singh, Ashok Kumar et al. · Hepatology · 2004 · 103 citations · Full text
Hepatic dysfunction in hyperthyroidism.
Saro Khemichian, Tse–Ling Fong · PubMed · 2011 · 58 citations
Medicine, Endocrinology, Pathology +10