Cell Reports · 2020 · 103 citations · 52 references
Life SciencesImmunologyOncologyCancer ImmunologyInflammationMolecular OncologyCell Cycle SignalingCell-cycle CheckpointsCell-cycle RegulationDna Damage SignalingImmune CheckpointsInflammatory SignalingCell Cycle Checkpoint DisruptionCell Cycle DisruptionCyclic Gmp-amp Synthase SignalingDamage-associated Molecular Pattern RecognitionG2 Checkpoint ArrestP53 InactivationP53-mediated Cell Cycle ArrestP53-mediated Cell-cycle Arrest
checkpoint. These findings link aberrant cell progression and p53 loss to an expanded spectrum of damage-associated molecular pattern recognition and have implications for the design of rational approaches to augment anti-tumor immune responses.
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The Molecular Signatures Database Hallmark Gene Set Collection
Arthur Liberzon, Chet Birger, Helga Thorvaldsdóttir et al. · Cell Systems · 2015 · 14.5K citations · Full text
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
Lijun Sun, Jiaxi Wu, Fenghe Du et al. · Science · 2012 · 4.8K citations